Dr. P. K. Das

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Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, Delhi 110076

Monday - Friday 08:00 - 20:00

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+91 98104 44600
Official Address

Indraprastha Apollo Hospitals

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bladder cancer specialist in Delhi

Each year approximately 275, 000 people are diagnosed with bladder cancer worldwide and 108, 000 people die of the disease. It ranks 10th among the most common cancers. While Greece, Lebanon, and Denmark top the list of countries with the most bladder cancer cases in the world, India is not very far behind. 

Bladder cancer is a nonlinear form of cancer, and it can manifest in multiple ways. Dr. P.K. Das, the best oncologist in Delhi NCR, and his team’s expertise in urology, medical oncology, urologic surgery, radiation oncology, pathology, and radiology has helped thousands of bladder cancer patients in the last 20+ years.

What is bladder cancer?

To understand bladder cancer, we first have to understand the bladder. A bladder is an essential organ of the human body; it is a hollow organ in the lower pelvis. The organ has flexible muscular walls; these walls can stretch to hold urine as well as squeeze it to dispel it out of the body. The bladder helps store urine-the liquid waste created by the two kidneys and then carried to the bladder through two connected tubes called ureters. When someone urinates, the bladder muscles contract, and the urine is forced out of the bladder through a tube called the urethra. As any cancer doctor in Delhi will tell you, bladder cancer starts when the cells making up the urinary bladder start to grow out of control. Without treatment or diagnosis, more cancer cells develop, and they form a tumor, which, with time, spreads to other parts of the body.

What are the 3 types of bladder cancer?

The type of bladder cancer is diagnosed based on how the tumor cells look under the microscope. The three types of bladder cancer are:

Urothelial Carcinoma

90% of bladder cancers are urothelial carcinoma or UCC. Not only that, but it also accounts for 10-15% of kidney cancers diagnosed in adults. It begins in the urothelial cells of the urinary tract and then spreads. UCC is also called transitional cell carcinoma or TCC.

Squamous Cell Carcinoma

If there is an irritation or inflammation in the bladder lining, squamous cells will develop. Over time, these cells have the potential of becoming cancerous. Squamous cell carcinoma accounts for about 4% of all types of bladder cancers.

Adenocarcinoma

Adenocarcinomas account for 2% of all bladder cancers. They develop from glandular cells in the body.

Different stages of bladder cancer

Stage 0

In this stage, the bladder cancer stays in the inner lining.

Stage 1

In this stage, cancer has spread to the walls of the bladder.

Stage 2

In this stage, cancer has reached the muscle of the bladder wall.

Stage 3

This is the stage in which cancer has spread to the fatty tissues around the bladder. It has also possibly spread to certain nearby lymph nodes. Not only that, but it may also have spread to the prostate in men or the uterus or vagina in women.

Stage 4

In this case, cancer has spread to the pelvic or abdominal walls, lymph nodes, or distant sites such as bone, liver, or lungs.

Bladder Cancer FAQs

Some warning signs of bladder cancer, according to any of the best medical oncologists in Delhi & the world are:

  • Blood in urine

Whether picked up by routine testing or visible, blood in urine can be a sign of bladder cancer (not always). In these cases, the urine may look a little darker than usual, maybe brownish or red (if rarely). More often than not, blood in the urine is not caused by cancer but by some other causes like trauma, infection, blood or kidney disorders, or drugs such as blood thinners. 

  • Bladder Changes

Changes in the bladder are more likely caused by conditions other than cancer. But bladder cancer too can cause certain changes like: 

-Feeling the need to urinate, with little or no results

-Having to urinate more often than usual

-Painful urination

-Difficulty urinating

NOTE: UTIs/Urinary tract infections or bladder stones can cause similar symptoms, but they require different treatments.

  • Burning sensation during urination

Burning sensation during urination can also be a symptom of bladder cancer. However, they can also be symptoms of UTIs or other infections. 

  • Lower Back pain

Lower back pain can be caused due to a myriad of reasons. However, lower back pain on one side can often occur due to bladder cancer.

 

Risk factors for bladder cancer

  • Smoking

For bladder cancer, smoking is the most important risk factor. Individuals smoking at least three times are more likely to get bladder cancer than those who don’t. 50% of all bladder cancers in both men and women are caused by smoking. 

  • Chemical Exposure

According to recent research, individuals doing certain jobs, like metal workers, mechanics, and hairdressers, may increase the risk for bladder cancer. Why? Because they are exposed to cancer-causing chemicals. So, if you work with colors/dyes or deal with rubber, textiles, or even paints, you should always follow the safety procedures to a T to reduce contact with dangerous cancer-causing chemicals. If you smoke, that can increase the risk of chemical exposures even more.

Apart from the above two major risk factors, there are other risk factors as well, like:

  • Gender: Men are 3 times more likely to get bladder cancer.
  • Age: 9 out of 10 cases of bladder cancer occur over age 55.
  • Race: Caucasians have 2 times the risk of African-Americans.
  • Those who have a family history of bladder cancer.
  • Previous cancer treatments.
  • Chronic bladder irritation.
  • Some of the birth defects of the bladder.

The pain of bladder cancer is often located in the lower abdomen, mostly on one side. 

 

Bladder cancer survival rates by age

 

Here are the 5-year survival rates for bladder cancer depending on age and stage of the disease. 


  • Localized Cancer

For localized cancer, the survival rate for people under the age of 50 is at 83%. For people between the ages of 50 to 64, the survival rate is at 80%. And lastly, for people 65 years and older, the survival rate is at 65%. 


  • Regional Cancer

For regional cancer, the survival rate for people under the age of 50 is at 43%. For people between the ages of 50 to 64, the survival rate is at 38%. And lastly, for people 65 years and older, the survival rate is at 35%. 


  • Distant Cancer

For regional cancer, the survival rate for people under the age of 50 is at 8%. For people between the ages of 50 to 64, the survival rate is at 7%. And lastly, for people 65 years and older, the survival rate is at 5%.

Multiple diagnostic tests & procedures are used to detect bladder cancer, mostly in combination. The procedure is selected based on both patient symptoms and risk factors. 

The tests & procedures include:

  • Urinalysis: This is a quick test. It is used to detect blood & other substances in the urine.
  • Urine cytology: In this test, the urine is examined through a microscope to see if cancer cells are present.
  • Genomic urine tests: These are non-invasive molecular tests. In these tests, non-invasive methods such as Cxbladder measure gene expression (sometimes referred to as ‘tumor markers’) to detect or rule out bladder cancer.
  • Cystoscopy: In this test, a thin & flexible tube with a light and camera, called a cystoscope, is inserted into the bladder through the urethra. If any abnormal area shows up, a small sample of tissue (a ‘biopsy’) is collected usually for laboratory examination.
  • Imaging: Many types of imaging tests are used to visualize the inside of the body, such as ultrasound, CT scan, MRI scan, and x-ray.

Bladder cancer treatments

Multiple types of therapy and treatments are used to treat bladder cancer. The treatment plan is chosen depending on the type & stage of bladder cancer, a patient’s overall health, and individual preferences. Some of the common cancer treatments in Delhi NCR, India, and the world include: 

  • Surgery

Through surgery, oncology surgeons remove tumor cells and the surrounding tissue. The kind of surgery used on individuals depends on different factors, such as the size and progression of the tumor.

  • Chemotherapy

Chemotherapy, widely known as chemo, involves a drug or a combination of drugs that kills cancer cells in the body. Patients may receive chemotherapy before or after surgery. It can be local (that is delivered directly into the bladder) or systemic (that is taken orally or by injection). 

 

  • Immunotherapy

Immunotherapy involves using either naturally occurring or lab-made substances to improve or bolster the cancer patient’s immune system so it can fight cancer.  Immunotherapy can also be delivered either locally or systemically. 

 

  • Radiation therapy

Radiation therapy uses x-rays or other high-energy waves or particles to target and kill cancer cells in a body.

The top oncologists in Delhi, India, & the world often use the popular chemo drug cisplatin to treat urothelial carcinoma, the most common type of bladder cancer. It is known to be the most effective. However, for other types of bladder cancers, other treatments or a combination of treatments are more effective.

Bladder cancer can be usually treated successfully if caught in the early stages. Later-stage bladder cancers pose greater challenges but are also manageable depending on staging and spread. There is a risk of recurrence for bladder cancer; that is why early detection is important.

The exact cause of bladder cancer is unknown. But smoking is the greatest risk factor for bladder cancer. So smokers are at the most risk. But workers in the rubber, chemical, and leather industries are also at risk. Some other people at risk are hairdressers, machinists, metal workers, painters, textile workers, and firefighters.

The symptoms of bladder cancer are generally the same in men and women. However, in women, the most common bladder cancer symptom-blood in urine-is commonly mistaken for menstruation and often overlooked. Men are more likely to notice blood in urine, so bladder cancer early detection is more common in men.

Blood in urine is the earliest and most common symptom of bladder cancer. Lower back pain and urinary incontinence can also be seen in some people at this stage.

80% of stage 1 bladder cancer patients survive at least 5 years or more after a bladder cancer diagnosis.

The survival rate for stage 4 bladder cancer is 5%.

40% of stage 3 bladder cancer patients survive at least 5 years or more after a bladder cancer diagnosis.

45% of stage 2 bladder cancer patients survive at least 5 years or more after a bladder cancer diagnosis.

The general 5-year survival rate for people with bladder cancer is 77%. This is a very good percentage. Many people live normal lives after bladder cancer diagnosis & treatment. So, if you or your loved one has been diagnosed with bladder cancer, there is no need to worry. If you need more information or guidance, you can always reach out to an expert, like Dr. P.K. Das, a top bladder cancer specialist in Delhi.